Amplification Method for Detecting Cardiac Troponin I with CRISPR/Cas13a Combined with Machine Learning by SERS
The paper published in ACS Applied Materials & Interfaces on 2026-10-27 reported that CRISPR/Cas13a induced by T7 RNA polymerase and branched HCR amplification were combined with machine learning to detect cardiac troponin I by SERS. From a materials and biosensing perspective, it is an example of combining multiple amplification with spectroscopic signal interpretation, but the specific machine learning model and performance metrics cannot be confirmed from the provided metadata alone.